CHE3704 - Analytical Chemistry III (Theory)

CHE3724 - Analytical Chemistry III (Practical): CHE3724

• Sample Preparation

• Green Chemistry

• Environmental Analytical Chemistry

• Food Safety

• Chromatography

• Spectroscopy

My research focuses on the development of environmentally sustainable microextraction sample preparation techniques and the synthesis of green solvents for the extraction and determination of organic pollutants, e.g., antibiotics, etc., and inorganic pollutants such as heavy metals in complex matrices.

The green microextraction methods are applied for the determination of pollutants in animal-derived food and agricultural products to ensure food safety.

Chromatographic and Spectroscopic methods are used for characterization.

• Tlou Makwakwa, Dineo Moema, Titus Msagati. Multi-criteria decision analysis–Technique for order of preference by similarity to ideal solution for selecting greener analytical method in the determination of mifepristone in environmental water samples. Environmental Science and Pollution Research (2024).
• Moema, TA. Makwakwa, H.N. Nyambaka, S. Dube, MM Nindi. Method development and optimization of liquid liquid microextraction based on the decomposition of deep eutectic solvent for the determination of Chromium (VI) in spinach: Assessment of the greenness profile using Eco-scale, AGREE, and AGREEprep. Food Analytical Methods (2024), https://doi.org/10.1007/s12161-024-02583-z.
• Moema, T.A. Makwakwa, B.E. Gebreyohannes, S. Dube, M.M. Nindi. Hollow fiber liquid phase microextraction of fluoroquinolones in chicken livers followed by high pressure liquid chromatography: Greenness assessment using National Environmental Methods Index Label (NEMI), green analytical procedure index (GAPI), Analytical GREEnness metric (AGREE), and Eco Scale. Journal of Food Composition and Analysis 117 (2023) 105131.
• A. Makwakwa, D. Moema, H. Nyoni, T.A.M. Msagati. Ranking of dispersive-extraction solvents pairs with TOPSIS for the extraction of mifepristone in water samples using dispersive liquid-liquid microextraction. Talanta Open 7 (2023) 100206.
• Moema, S Dube and MM Nindi. 2022. Greener Surfactant-Assisted Microextraction Method for the Determination of Fluoroquinolones in Chicken Livers by High-Performance Liquid Chromatography. Anal. Chem. Lett. (2022), 12 (DOI: 10.1080/22297928.2022.2038668).